Our Technology
We combine advanced computational methods with cutting-edge experimental techniques to develop novel therapeutic approaches to aging, with a special focus on cell immortalization and transferable longevity factors.
Data Sources & Fine-Tuning
Advanced AI-driven mutation prediction and target identification using state-of-the-art models and comprehensive databases.
- •Evo2 (ARK Institute) base model for mutation target prediction
- •COSMIC Database integration for oncogenic region avoidance
- •Aging Atlas / GenAge data for pro-longevity loci identification
- •Probability distribution mapping of mutation hotspots
Reinforcement Learning Strategy
Sophisticated RL agents for adaptive mutation strategy generation and optimization based on experimental feedback.
- •Stable Baselines3 PPO/DQN implementation
- •Mutation strategy vector generation
- •Region-specific mutation intensity control
- •Adaptive targeting based on experimental results
Guide RNA Design System
Automated workflow for guide RNA design and synthesis, integrating multiple tools for optimal targeting.
- •n8n workflow automation pipeline
- •CHOPCHOP integration for efficient sgRNA selection
- •Benchling API for commercial-grade synthesis
- •Dual-purpose gRNA pools for mutation and protection
"0K BIO's platform is not just faster evolution—it's smarter evolution. By combining hypermutation, ML-guided constraint design, and synthetic population controls, we solve aging's complexity while preempting risks that nature never had to face.
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Research & Innovation
Publications (e.g)
Novel Approaches to Longevity Enhancement Through Synthetic Biology
Kenan Oggad, et al.
A comprehensive study on the application of synthetic biology techniques in longevity research.
Machine Learning Applications in Gene Therapy Optimization
Kenan Oggad, et al.
Novel machine learning approaches for optimizing gene therapy delivery and efficacy.
Patents (e.g)
Method and System for Adaptive Gene Therapy Delivery
GrantedKenan Oggad, et al.
A novel system for delivering personalized gene therapies using adaptive algorithms.
Artificial Intelligence System for Longevity Pathway Analysis
PendingKenan Oggad, et al.
An AI-driven system for analyzing and identifying key pathways in cellular aging.